What is Synthroid?

Synthroid is a prescription medication that can help treat hypothyroidism. The active ingredient in Synthroid is called levothyroxine sodium. Synthroid can help restore thyroid hormone balance. It is a man-made thyroid hormone identical to thyroxine, the hormone that’s naturally made by the thyroid gland.

Synthroid is a narrow therapeutic index (NTI) medication. With NTI medications, if your dose is off even a little bit, your TSH level may change. Because of this, your doctor will carefully titrate your dose because it is important to avoid under-replacement (not enough medicine) or over-replacement (too much medicine). Generally, hypothyroid medication is to be taken for life.



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    • Thyroid hormones, including SYNTHROID, should not be used for the treatment of obesity or weight loss. Large doses of thyroid hormone, especially when used with certain drugs that reduce appetite, can result in serious and even life-threatening effects.
    • Do not use SYNTHROID if you have uncorrected adrenal problems.
    • Excessive amounts of levothyroxine sodium therapy have been associated with decreased bone strength, especially in women after menopause.
    • Talk to your doctor about all medications you are taking, pregnancy plans, and all medical conditions you may have, especially heart disease, diabetes, blood clotting problems, and adrenal or pituitary gland problems. The dose of other drugs you may be taking to control these conditions may have to be changed while you are taking SYNTHROID. Tell your doctor if you are taking SYNTHROID prior to any surgery.

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